We provide microgels with different shapes, sizes, physical and chemical properties as the materials building blocks for 3D tissue architecture. They are made of linear or star polyethylene glycol (PEG) and can be functionalized for cell adhesion and signaling. Additionally, they can be tuned for alignment or on-demand degradation.
How you can use it:
You can use it in two different ways:
- Microgels with cells for self-assembly into a microgel-based scaffold. This system is suitable when you let cells self-organize and build their own home. Use it especially when your model contains any stem cells.
- Our system provides key advantages across several critical aspects, including: Microgels embedded in another cell-laden hydrogel or matrix. This system is suitable for making your 3D culture system anisotropic, i.e. giving direction to cell migration, elongation, growth, and signaling.
Key advantages of microgel-based scaffolds:
Our platform provides key advantages across several critical aspects, including:
- Enhanced oxygen and nutrient diffusion
- Precise control over tissue size and architecture
- Greater cellular freedom for self-assembly into native tissue structures
- High experimental reproducibility
- Decoupling of biochemical and mechanical cues
- Compatibility with automated manufacturing and high-throughput workflows